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Neural decoding : ウィキペディア英語版
Neural decoding
Neural decoding is a neuroscience-related field concerned with the reconstruction of sensory and other stimuli from information that has already been encoded and represented in the brain by networks of neurons. Reconstruction refers to the ability of the researcher to predict what sensory stimuli the subject is receiving based purely on neuron action potentials. Therefore, the main goal of neural decoding is to characterize how the electrical activity of neurons elicit activity and responses in the brain.
This article specifically refers to neural decoding as it pertains to the mammalian neocortex.
== Overview ==
When looking at a picture, our brains are constantly making decisions about what object we are looking at, where we need to move our eyes next, and what we find to be the most salient aspects of the input stimulus. As these images hit the back of our retina, these stimuli are converted from varying wavelengths to a series of neural spikes called action potentials. These pattern of action potentials are different for different objects and different colors; we therefore say that the neurons are encoding objects and colors by varying their spike rates or temporal pattern. Now, if someone were to probe the brain by placing electrodes in the primary visual cortex, they may find what appears to be random electrical activity. These neurons are actually firing in response to the lower level features of visual input, possibly the edges of a picture frame. This highlights the crux of the neural decoding hypothesis: that it is possible to reconstruct a stimulus from the response of the ensemble of neurons that represent it. By this we mean, it is possible to look at spike train data and say that the person or animal we are recording from is looking at a red ball.
With the recent breakthrough in large-scale neural recording and decoding technologies, researchers have begun to crack the neural code and already provided the first glimpse into the real-time neural code of memory traces as memory is formed and recalled in the hippocampus, a brain region known to be central for memory formation.〔Chen G, Wang LP, Tsien JZ. Neural population-level memory traces in the mouse hippocampus. PLoS One. 2009 Dec 16;4(12):e8256. doi: 10.1371/journal.pone.0008256.PMID 20016843. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0008256 〕〔Zhang H, Chen G, Kuang H, Tsien JZ.Mapping and deciphering neural codes of NMDA receptor-dependent fear memory engrams in the hippocampus.PLoS One. 2013 Nov 26;8(11):e79454. doi: 10.1371/journal.pone.0079454. eCollection 2013.PMID: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.007945424302990 〕 Neuroscientists have initiated large-scale brain activity mapping or brain decoding project 〔The Brain Decoding Project. http://braindecodingproject.org/〕 to construct the brain-wide neural codes.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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